Police say the bus was headed to Centennial Elementary School at about 8:30 a.m. ET when the crash occurred.
The bus was traveling south on Centennial Lane when it hit the van.
The driver and five students were taken to Howard County General Hospital with minor injuries.
The driver of the van and two of its passengers were also taken to the hospital with injuries. The driver of the other vehicle was uninjured.
No citations have yet been issued but the crash remains under investigation.
The names of the drivers and the ages of the children involved have not been released.