The accident took place at about 4:15 p.m. ET on Sunday afternoon on Indian Head Highway.
Officers say Derico Cordora Lynch, 26, of Accokeek, was driving south when he lost control of his car and hit another vehicle.
Lynch’s car reportedly crossed over the median strip and struck a motorcycle and a truck before coming to a stop.
Lynch was pronounced dead at a nearby hospital.
The driver and passenger of the truck were released after receiving treatment.
The accident is under investigation at this hour.